cliffwatch

Recent changes

Every event cliffwatch detected on a reference-listed drug: generic-entry dates that moved, patents listed or delisted, exclusivities granted, generics approved. Dates are as listed in the FDA Orange Book; the detection date is when the change appeared in FDA's files.

Last
  • 26 Oct 2026Loperamide Hydrochloride · Generic approved · 021855-001
  • 26 Oct 2026Adrenalin · Generic approved · 204200-001
  • 26 Oct 2026Adrenalin · Generic approved · 204200-001
  • 26 Oct 2026Lanreotide Acetate · Generic approved · 215395-001
  • 26 Oct 2026Asacol Hd · Generic approved · 021830-001
  • 26 Oct 2026Isopto Atropine · Generic approved · 208151-001
  • 26 Oct 2026Renova · Generic approved · 021108-001
  • 26 Oct 2026Dificid · Exclusivity expires within 90 days ODE-367 · 201699-001
  • 26 Oct 2026Dificid · Exclusivity expires within 90 days ODE-367 · 213138-001
  • 25 Oct 2026Omnipred · Generic approved · 017469-001
  • 25 Oct 2026Ortho Tri-Cyclen · Generic approved · 019697-001
  • 25 Oct 2026Calcium Gluconate · Generic approved · 208418-001
  • 25 Oct 2026Bexlutry · First generic approved · 218525-001
  • 25 Oct 2026Bexlutry · Generic approved · 218525-001
  • 25 Oct 2026Sunosi · Generic tentatively approved · 211230-001
  • 25 Oct 2026Sunosi · Generic approved · 211230-001
  • 25 Oct 2026Nexium · Generic approved · 022101-001
  • 25 Oct 2026Phenylephrine Hydrochloride In 0.9% Sodium Chloride · Generic approved · 216830-001
  • 25 Oct 2026Absorica Ld · Generic approved · 211913-001
  • 25 Oct 2026Atropine Sulfate · Generic approved · 206289-001
  • 25 Oct 2026Sprycel · Generic approved · 021986-001
  • 25 Oct 2026Tazverik · Exclusivity expires within 90 days ODE-299 · 211723-001
  • 25 Oct 2026Zynrelef Kit · Exclusivity expires within 90 days I-933 · 211988-004
  • 25 Oct 2026Zynrelef Kit · Exclusivity expires within 90 days I-933 · 211988-003
  • 25 Oct 2026Zynrelef Kit · Exclusivity expires within 90 days I-933 · 211988-002
  • 25 Oct 2026Zynrelef Kit · Exclusivity expires within 90 days I-933 · 211988-001
  • 25 Oct 2026Azulfidine · Generic approved · 007073-001
  • 25 Oct 2026Avapro · Generic approved · 020757-001
  • 25 Oct 2026Victoza · Generic approved · 022341-001
  • 25 Oct 2026Brilinta · Generic approved · 022433-001
  • 25 Oct 2026Mycobutin · Generic approved · 050689-001
  • 25 Oct 2026Mektovi · Generic tentatively approved · 210498-001
  • 25 Oct 2026Xeljanz Xr · Generic approved · 208246-001
  • 25 Oct 2026Fludarabine Phosphate · Generic approved · 022137-001
  • 25 Oct 2026Zembrace Symtouch (Autoinjector) · Generic approved · 208223-001
  • 25 Oct 2026Vibramycin · Generic approved · 050442-001
  • 25 Oct 2026Ocuflox · Generic approved · 019921-001
  • 25 Oct 2026Zyprexa · Generic approved · 021253-001
  • 25 Oct 2026Ravicti · Generic approved · 203284-001
  • 25 Oct 2026Tricor · Generic approved · 021656-001
  • 25 Oct 2026Invega · Generic approved · 021999-001
  • 25 Oct 2026Xeljanz · Generic approved · 203214-001
  • 25 Oct 2026Abilify · Generic approved · 021713-001
  • 25 Oct 2026Afinitor · Generic approved · 022334-001
  • 25 Oct 2026Vasostrict · Generic approved · 204485-001
  • 25 Oct 2026Venclexta · First generic approved · 208573-001
  • 25 Oct 2026Venclexta · Generic approved · 208573-001
  • 25 Oct 2026Benicar Hct · Generic approved · 021532-002
  • 25 Oct 2026Tambocor · Generic approved · 018830-001
  • 25 Oct 2026Calcium Gluconate In Sodium Chloride · Generic approved · 210906-001

Public history covers the last 365 days. Watch a drug or company for alerts the day a date moves; the API plan serves the full append-only stream. cliffwatch reports regulatory facts and is not investment advice.